Home
Tutorials
Can you believe it?
Hot Topics
Great Links
About this site
Can you believe it?



Picture this: You're at the dentist's office and a
technician squirts a mouthwash containing
genetically modified bacteria onto your teeth. You
wait a few minutes, eat some sugar to help
colonize the new bacteria and from this day on, no
more cavities. This is the scenario that
researchers at the University of Florida are hoping
to fulfill one day soon. We have long known that
most cavities are caused by the activities of
Streptococcus mutans. This bacteria eats sugar
deposited on teeth and converts it into lactic acid,
which erodes tooth enamel and causes cavities.
To combat S. mutans, scientists created a new
bacterial strain, called BCS-LI. They started by
isolating a naturally occurring strain of S. mutans
which produces an antibiotic that kills other
strains of S. mutans. Then they modified this
strain by deleting the gene encoding lactate
dehydrogenase, the enzyme which makes lactic
acid from sugar. After just one treatment, the
super Strep should keep your mouth free of
lactic acid producing Strep and free of cavities!



Imagine an organism that can withstand severe
drought, frigid temperatures and lethal levels of
radiation. These are just a few of the properties of
Deinococcus radiodurans, a microbe listed in the
Guinness Book of World Records as "the world's
toughest bacterium." This microbe was first
identified in a can of meat that spoiled despite the
fact that it had been sterilized by radiation. Exposure
to high levels of radiation causes breaks to occur
within strands of DNA. Organisms rely on repair
enzymes to fix the breaks, but these repair
mechanisms have their limits. So what gives D.
radiodurans the ability to deal with huge doses of
radiation? The secret lies in the structure of its
genome. While other bacteria have only 1 copy of
their DNA, D. radiodurans has 4. Most importantly,
the DNA is packed in a tight ring, which prevents
the DNA pieces from floating off into other parts
of the cell. This allows the microbe to quickly and
accurately rebuild its DNA. Researchers hope to
use D. radiodurans to help clean-up
radioactively contaminated sites.


Scientists in Japan have created a genetically
engineered silkworm that expresses the human
protein collagen. Collagen is a structural protein
that allows tissues to maintain their shape.
As the modified silkworm weaves its cocoon,
it not only spools out threads of silk, it also
spool out threads of collagen. Because silk
is made from a natural protein, the silk and
collagen proteins can be easily isolated by
heating the cocoon and unwinding the silk
filament. The collagen is then separated from
the silk and can be used therapeutically to
generate artificial skin or wound dressings.
Traditionally, recombinant collagen has been
synthesized in microorganisms in a process
that is both expensive and time consuming.
Therapeutic collagen has also been isolated
from cow tissues, but this type of collagen often
causes an allergic reaction in patients.
Silkworms are able to spin a cocoon in just 3
days and may offer a cheaper and faster means
for synthesizing therapeutic proteins.




Scientists have been using plants to mop
up pollutants from soil for a while now.
However, this process, known as
phytoremediation, has been hindered by the
fact that few naturally occurring plants grow
well in polluted soils. To give Mother Nature a
little help with cleaning-up arsenic
contaminated soils, scientists have modified
thale cress plants (a small weed related to
mustard plants) to include 2 genes from
E. coli. The first gene enhances the plant's
natural ability to take up arsenate. The second
gene helps the plants bind more tightly to
arsenate, making this compound less bio-
available and thus less toxic to the plants.
The result is a plant that grows well in arsenic
polluted soils and which has the ability to
remove arsenic from the soil at a rate three
times faster than that of unmodified plants.
Once the arsenic has been concentrated in
the plants' tissues, the plants can be safely
incinerated. Down the road, researchers hope
to turn large trees into soil-cleaning machines.



Sharks very rarely develop cancer. For this reason
some people have taken to eating shark cartilage
with the hope that this will help treat their cancer.
Shark cartilage does contain a substance called
angiogenin inhibitor which acts by preventing
blood vessels from forming near a tumor. Without
blood vessels, nutrients can't flow into the tumor
and waste products can't leave. So, the tumor
cells shrivel up and die. But eating shark cartilage
won't help humans fight off cancer because the
angiogenin inhibitors can't pass through our gut
wall. Also, the sharks' resistance to developing
tumors is more likely due to their primitive, but
very potent immune system, rather than to
the action of angiogenin inhibitors.


Have you ever eaten a genetically modified (GM)
food? The answer is probably yes. By current
estimates, about 70% of the food on supermarket
shelves contains at least a small amount of
genetically altered plant material. Corn and
soybeans are the primary sources of GM
ingredients. GM corn may be added to foods in
the form of corn syrup or cornstarch. Soybean-
based ingredients include oil, flour and protein
extracts. Some foods may also contain GM cannola
oil (e.g., cookies,margarines and fried foods) or
GM cottonseed oil (e.g. chips and salad dressings).
In the U.S., labeling of GM crops is required only if the
food differs with respect to its safety, composition or
nutritional value as compared to conventional
foods. Currently there are no GM foods on the
market in the US which fall into this category.

Ever wonder why lakes and oceans
don't freeze solid? When most
substances solidify, they contract and
become denser. But, water is one of the
few substances that expands as it
solidifies, making it less dense as a solid
than as a liquid. In fact, ice is about 10%
less dense than liquid water. The ability
of ice to float is essential to maintaining
aquatic life. When lakes and oceans
cool, the ice that floats on top helps
insulate the water below, preventing it from
freezing and protecting the animals and
plants living below the frozen surface.


At one time, stonewashed jeans were made by
literally washing cotton material with pumice stones.
The stonewashing process weakens the cotton
fibers producing a soft, faded look. But, the process
also quickly wears out the fabric, seriously damages
washing machines and requires many cycles of
rinsing to remove the stones. Now, thanks to an
innovative biotechnology approach, a more
environmentally friendly and cheaper way to make
faded jeans has been developed. The new process
makes use of microbially synthesized cellulose
enzymes. The enzymes help break down the
cellulose fibers of cotton, without damaging the fabric.
Bio-stonewashing produces the same great worn look
with the added benefits of using less water & energy.

 

We can learn a lot about science by cooking an egg.
For instance, you've probably noticed that egg whites
start off clear and colorless, but turn white when
cooked. This is because in their native state the
proteins in egg whites are completely dissolved in
fluid. Upon heating, the proteins become denatured
and unwind. New protein bonds eventually form,
producing a tighter more intricately connected mass.
The clusters of proteins now deflect light rays and
the egg whites appear opaque. When cooking eggs
it is best to use moderate heat since high heat
causes the eggs to become tough and rubbery. The
mechanical energy exerted by whisking causes a
similar effect in which protein bonds break and a
new network of cross-linking bonds form, allowing
the egg whites to form soft peaks.


How much sleep do you need?

The average human sleeps about 8 hours a
day - that's around 25 years of sleep over a life
span of 75 years. As you might expect,
cats sleep away about half of the day. Some
animals need even more sleep, with lions
sleeping about 14 hours a day and squirrels
sleeping almost 15 hours a day. The giant
armadillo sleeps a whopping 18 hours each
day. Other animals need less sleep - cows
sleep only about 4 hours a day, horses
about 3 hours a day and giraffes just about
2 hours a day. Sleep helps to restore our bodies
and may be important for memory and learning.